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Pan SW et al

Surgery carries surgical risks and requires permanent dietary modifications

Together, these findings demonstrate that, in contrast with acute exposure, chronic disruption of iron homeostasis with consequent GSH depletion remodels cellular redox homeostasis over time, inducing a state we term chronoferroptosis: a persistent ferroptotic adaptation characterized by coordinated alterations in iron-handling and antioxidant defense proteins that may represent early vulnerability to neurodegenerative pathology

This innovative solution is administered via subcutaneous injection or nasal spray and is still undergoing research to assess its effectiveness and safety for clinical use