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It also compounds the risk of functional decline and bone density loss, which is the opposite of what a longevity-focused patient is working toward
The linkage between PEG and the drug molecule can be either stable or degradable, the latter being commonly used for prodrugs
Eli Lilly's orforglipron, a daily GLP-1 pill, could be available as soon as next year and would eliminate the need for injections
This means that both the onset of full effect when starting treatment and the waning of effect when stopping treatment may take several weeks
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