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98 One approach involves the autoregulated overexpression of key cell cycle regulators, 99,100 including CDK1, CDK4, CCNB1, and CCND1, which have been shown to induce 1520% proliferation of mature cardiomyocytes and improve post-MI outcomes
As currently there is not enough information about the safety of GLP1-RAs during pregnancy, it is recommended to stop GLP1-RAs when planning pregnancy
Regulatory note: The FDA has issued warning letters to compounding pharmacies and online sellers offering growth hormone secretagogue peptides including GHRP compounds
Umpierrez, G
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