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The evidence includes STEP (semaglutide, The New England Journal of Medicine , 2021), SURMOUNT (tirzepatide, NEJM 2022), and SURMOUNT-OSA (NEJM 2024)
8.1 Challenges in the optimization of multi-receptor agonists Although multi-receptor agonists such as tirzepatide exhibit enhanced effectiveness, their development poses distinct obstacles that need careful attention
Almost certainly yes, with requirements
The general rule is to keep unopened semaglutide vials refrigerated until you are ready to use them
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