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How to Manage Nausea from GLP-1 Drugs If youre experiencing nausea while on GLP-1 therapy, consider the following tips to find relief: Start with a Low Dose and Increase Gradually Many patients find that starting with a lower dose and gradually increasing it helps their body adjust to GLP-1 medications

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[57] It suppresses appetite through a dual mechanism: it directly stimulates anorexigenic (satiety-inducing) neurons that express proopiomelanocortin (POMC) and cocaine-and amphetamine-regulated transcript (CART), while simultaneously inhibiting orexigenic (appetite-inducing) neurons that express AgRP and NPY