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In contrast to GLP-1 mono-therapy, GLP-1/estrogen co-agonism prevented hyperphagia and beta-cell failure in NZO mice (Schwenk et al., 2014)
Amino Acids 51:103114 Food and Drug Administration (FDA), Center for Drug Evaluation and Research (CDER), U.S
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This effect can lead to heartburn in some people using Mounjaro for weight loss, particularly when starting treatment or increasing the dose
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