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In murine models of bleomycin-induced lung injury, genetic deletion of the GLP-1 receptor was associated with reduced inflammatory injury, and pharmacological GLP-1 receptor activation exacerbated pulmonary inflammation [71]
Gallbladder Disease and Biliary Risks GLP1 medications have been linked to a slightly increased risk of gallbladder disease, including gallstones and cholecystitis
Key Takeaways Several drugmakers are working on oral GLP-1s, offering people with obesity and overweight more options than the injectables on the market
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It may also appeal to patients who are newer to GLP-1 medications and want a well-established medication pathway before considering a more potent dual-action option
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