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These medications remain expensive, costing more than $16,000 per patient per year for some patients, and employers, health plans, and patients are feeling it
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Glutathione production in cells declines naturally at an average rate of 10% per decade after age 20
Comparisons With Other Diabetes Therapies Putting GLP1s in context with other antidiabetic agents offers additional insights: Thiazolidinediones (TZDs) are associated with increased fracture risk, especially in women SGLT2 inhibitors have raised concerns in some trials, particularly canagliflozin DPP-4 inhibitors appear largely neutral regarding skeletal effects Against this backdrop, GLP1s may have a neutral or possibly safer profile, though the data are not conclusive
