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With the popularity of GLP-1 drugs skyrocketing, it is likely that the analysis of these drugs will be more prolific than ever

A study in the JAMA Network showed that tirzepatide, the active ingredient in Zepbound and Mounjaro, helped overweight or obese adults lose an average of over 20% of their body weight

Indeed, research found that supplementing with 2grams of L-carnitine + 80g carbohydrate twice daily for 24 weeks saw an increase in fatty acid utilisation, substantially reduced lactate production and an increased work output of 11% from baseline when compared to no change in the control group 7

However, some users may experience side effects, which typically resolve on their own or with dose adjustment: If any side effects occur, reducing the dose or temporarily discontinuing use is usually effective