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Both of these fall within the C11-C24 feeding window

In diet-induced obese mice, chronic Retatrutide dosing produced greater reductions in adipose mass and food intake than matched-exposure Semaglutide or Tirzepatide comparators, with indirect calorimetry showing increased energy expenditure attributable to the GCGR component and reduced hepatic triglyceride content on histology

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In addition, activation of GLP-1R in the brain is albe to reduce appetite, lowering the risks for other diseases such as metabolic and cardiovascular disorders (88)