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Copper Peptide Products Versus Retinoids and Cosmetic Actives Cu-GHK has been compared with vitamin C and retinoic acid in a small collagen-production context summarized in a topical peptide review, where collagen increased in 70% of Cu-GHK-treated participants versus 50% with vitamin C and 40% with retinoic acid after one month [2]

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As this new collagen builds over months, it restores volume and firmness to the skins structure

Karuppagounder SS, Alin L, Chen Y, Brand D, Bourassa MW, Dietrich K, Wilkinson CM, Nadeau CA et al (2018) N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E 2 to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice