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Patients with pernicious anemia have an irreversible cause of deficiency, so its important to ensure other factors do not contribute to further deficiency progression

While animal studies cannot definitively rule out human cancer concerns, the consistent absence of tumors or pre-cancerous changes across multiple species, dosing regimens, and administration routes carries meaningful weight

10.1016/j.ijscr.2024.109931 9 CaballeroM.LukawskaJ.LeeT.DuguP

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