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While often mild, the nausea is dose dependent and limits the use of higher doses to drive greater weight loss [35]
"You have to think about this as chronic disease management, not responding to a TikTok trend." Rekha Kumar, M.D., Found's chief medical officer and a specialist in obesity medicine, said that the increased attention and demand for drugs like Ozempic and Wegovy are leading payers to look far more closely at prescriptions and deny coverage more frequently
The study was designed as proof of concept for NNMT as a drug-development target
GLP-1 medications may affect appetite and satiety pathways in some patients, but individual response varies
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