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These findings highlight microglia as promising therapeutic targets at the intersection of neuroinflammation and cardiovascular pathology
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Using an aging ovariectomized rat model they found supplementation of L-carnitine can influence bone density and slow the rate of bone turnover by slowing bone loss and improving bone microstructural properties through decreasing bone turnover [154]
Given the observed changes in the respiratory quotient and perceived exertion, further studies could also explore the underlying biochemical mechanisms responsible for these effects, such as the role of L-carnitine in mitochondrial function, fat oxidation, and glycogen preservation during prolonged exercise
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