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4 Discussion In this study, by using genetic variants as unconfounded proxies for the GLP-1RAs, we attempted to disentangle relationships between GLP-1RAs and ED risk

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They found that hyperammonemia was an independent predictor of hospitalization with liver-related complications and mortality, superior even to the Child-Pugh classification and the Model for End-stage Liver Disease (MELD) score

For these patients, an individualised risk assessment before or shortly after starting treatment is worthwhile