Its short half-life, however, required it to be injected several times a day, which limited its appeal as a drug, and the company ran out of funding
Common Symptoms of Insulin Resistance While lab testing can confirm insulin resistance, many people experience symptoms such as: Constant fatigue or energy crashes after meals Difficulty losing weight, especially belly fat Sugar or carb cravings Brain fog and poor concentration Increased hunger, even after eating Elevated fasting glucose or A1C levels Skin darkening on the neck, armpits, or groin (acanthosis nigricans) If these sound familiar, your body may be signaling that insulin resistance is at play
You'll need to be over 18, and living in either Alberta, British Columbia, Manitoba, Ontario, or Saskatchewan
Generic orforglipron, when it eventually becomes available, could see pricing discounts of 80-90% below brand, following the pattern seen with other generic small molecules