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8 November 2023
Quality of life reports often indicate patients feel better on GLP-1 RA due to weight loss and better control, despite the nuisance of transient nausea
Application of liraglutide reduced mitochondrial damage by attenuating mitophagy via the protein phosphatase and tensin homolog-induced kinase 1 (PINK1)/Parkin pathway, the most well-known pathway for mitophagy (Figure 3)
This was done by performing a bilateral transection of the pudendal nerves and inhibiting NO synthase using L-NAME
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