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Manfredi Rizzo is former Director, Clinical Medical & Regulatory Department, Novo Nordisk Europe East and South and has given lectures, received honoraria and research support, and participated in conferences, advisory boards and clinical trials sponsored by pharmaceutical industry including Amgen, AstraZeneca, Boehringer Ingelheim, Kowa, Eli Lilly, Meda, Mylan, Merck Sharp & Dohme, Novo Nordisk, Novartis, Roche Diagnostics, Sanofi and Servier
LY3437943 may cause greater weight loss than Tirzepatide , a dual GIPR and GLP-1R agonist that has shown improved weight loss compared to selective GLP-1R agonists in patients with type 2 diabetes
3,4 American Association of Clinical Endocrinology guidelines recommend treatment with GLP-1RA in T2DM patients with coexisting ASCVD, high-risk for ASCVD, heart failure, or chronic kidney disease regardless of their glycemic control due to their organ protective effects
Semaglutide is not a one-size-fits-all solution, but for the right candidate, it can be a valuable tool within a structured, medically supervised weight loss program
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