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27 Free radical generation In addition, NADPH is also responsible for the generation of free radicals by NADPH oxidases (NOX) as a substrate
Patients should be provided with clear safety advice , including when to temporarily discontinue SGLT2 inhibitors (during acute illness, dehydration, or 3 days before surgery), recognition of DKA symptoms (nausea, vomiting, abdominal pain, unusual fatigue), and management of genitourinary infections
At the same time, Medicare is prohibited from covering these drugs if intended for weight loss only
Increased blood glucose levels: Since Ozempic and Mounjaro are designed to regulate blood glucose levels for patients with Type 2 diabetes, blood sugar can rise after stopping these medications
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