For normally distributed data a mixed linear model (MLM) was used, (as laid out by IBM in their SPSS Statistics guidelines, with mice IDs as subject variable and random effects, sex and APOE genotypes as factors, and age as a covariate
What the Regulatory Classification Tells Us These medications have historically been treated similarly to Pregnancy Category C drugs: animal studies showed potential risks, and we dont yet have robust human data to know what that means for human pregnancies
Semaglutide is approved as Ozempic (diabetes, December 2017), Wegovy (obesity, June 2021), and, in oral form, the Ozempic pill (diabetes, 2026, which reformulated and renamed Rybelsus) and the Wegovy pill (weight, December 2025)
"The antioxidant glutathione peroxidase family and spermatozoa: a complex story"