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Common B12 deficiency symptoms include fatigue, anxiety, depression, poor memory, confusion, brain fog, tingling or numbness in the extremities, zings or zapping feelings in the extremities, anemia, shortness of breath, muscle weakness, irritability, tender calves, pale complexion and more
Mediation analysis assessed the role of metabolites, and PheWAS evaluated potential side effects
doi: 10.1038/mp.2014.163 76 Ben-SkowronekISzewczykLKulik-RechbergerBKorobowiczE
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