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Vasiliou, V., Pappa, A
Intervention with different concentrations of sodium fluoride in osteoblasts led to an increase in intracellular ROS levels, a decrease in proliferation, and cell cycle arrest at the S phase (DNA synthesis phase), suggesting that sodium fluoride may suppress proliferation and block cell growth by increasing oxidative stress (38)
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Injectable administration is generally preferred when maximizing potency, dosing precision, and consistent therapeutic response is the primary goal
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