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Supplementation with N-acetylcysteine and taurine failed to restore glutathione content in liver of streptozotocin-induced diabetics rats but protected from oxidative stress

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GSH concentrations in tumor tissues are higher than that in the blood circulation system and normal tissues, as is reported that tumor tissues exhibits at least fourfold GSH concentration compared with normal tissues (15 mol/L), and the intracellular GSH concentration is then much higher and can reach up to 210 mmol/L (He et al