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J Bone Miner Res (2013) 28(7):164152
The pathophysiology of neuropathic pain varies and includes ectopic activity in damaged nerves or in adjacent nerves, dorsal root ganglion (DRG) or central pathways, and peripheral and central sensitisation involving numerous molecular mechanisms
Specifically, an imbalance between oxidants and antioxidants, increased ROS production, a reduction in antioxidant enzymes function contribute to the pathogenesis and development of psoriasis [3]
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