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The direction of modulation is notable: many genes associated with DNA repair, antioxidant response, and tissue remodeling are upregulated, while genes linked to inflammation and tumor progression are downregulated
doi: 10.1038/s41586-025-08974-4 123 RadadiyaPSThorntonMMPuriRVYerrathotaSDinh-PhanJMagenheimerBet al
Ipamorelin mimics ghrelin and has a strong effect on growth hormone (GH) and insulin-like growth factor 1 (IGF-1)
The intent behind its design was to influence fat metabolism without driving tissue growth or affecting insulin sensitivity the way full growth hormone can
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