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When ML models are trained on multi-country datasets using uniform preprocessing, cross-cohort transfer performance increases, suggesting the existence of resilient PD signatures but the need for large, standardized training sets [189]
Neither showed any effect on the primary endpoint, the Clinical Dementia Rating-Sum of Boxes at 104 weeks, nor on secondary cognitive and functional scales, and a pooled analysis found no delay in progression from mild cognitive impairment to dementia (hazard ratio 0.96) [1]
Deng, M
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