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Seek medical advice if you experience: New or worsening vision problems Severe or progressive weakness Loss of coordination or balance Confusion or cognitive changes Seizures These symptoms could indicate underlying conditions requiring investigation

PMID 34199569

Understand the tradeoffs

Clinical trials of FDA-approved semaglutide and tirzepatide show the difference clearly: Semaglutide patients lose about 15% of total body weight Tirzepatide patients lose approximately 21% Both medications can cause mild gastrointestinal side effects, but tirzepatide is often better tolerated, with many patients reporting fewer symptoms