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In similar clinical trials, semaglutide has been shown to reduce body weight by roughly 15 percent (34 pounds) after 68 weeks
It can take time to see results, and some people may not experience any noticeable changes
[1] [2] These results represent a degree of weight reduction not previously observed with any pharmacological agent in a trial of this duration, though Phase 3 data are required before firm conclusions can be drawn
TRIUMPH-1 reported continued loss in a prespecified extension for participants with baseline BMI of at least 35, but maintenance after discontinuation, long-term adverse events, and real-world adherence remain open questions [7]
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