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Carnitine administration to juvenile visceral steatosis mice corrects the suppressed expression of urea cycle enzymes by normalizing their transcription

This is the data behind the muscle-and-nutrient concern, drawn from the largest claims analysis to date , Butsch and colleagues' retrospective study of 461,382 US adults newly prescribed GLP-1RAs (Butsch et al., Obesity Pillars, 2025

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure