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158 In a crossover trial in 30 men between 41 and 60 years of age with DHEA-S levels below 200 mcg/dL, 40 days of treatment with 150 mg of DHEA per day resulted in a 4.5-fold increase in DHEA-S levels and improved a range of cardiometabolic markers compared with placebo

Any intervention producing significant weight loss, whether dietary, surgical, or pharmaceutical, carries elevated gallstone risk

It should be noted that men with known conditions that would cause inflammation (such as genital tract infections, varicocele) or that used alcohol, smoked, or were currently taking antioxidants were all excluded from the study to create a more consistent base-line of existing oxidative stress (inflammation) between the groups This study also showed that the higher the measured levels of ROS, the more damage there was to sperm function

This stability allows BPC-157 to remain active in harsh environments, including gastric acid, for over 24 hours