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However, most methods of obtaining darker coloured skin offer no health benefits and can lead to unpleasant side effects or life-threatening conditions in some cases.

J Neurosc 21(18):70697078 Elke G, Katrin H, Yvette N, Hermann H (2000) Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of Ras-dependent and -independent pathways

J Oral Maxillofac Surg 73:19461956 Borello ED, Gorlin RJ (1966) Melanotic neuroectodermal tumor of infancy: a neoplasma of neural crest origin

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