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GLP-1RA medications are the first pharmacotherapy for obesity with demonstrable cardiovascular benefits and ASCVD risk reduction

Diabetes2006 Jun;55(6):1755-60

Role of GLP-1 agonists in managing comorbidities in HFpEF Beyond their cardioprotective properties, GLP-1 receptor agonists exert a beneficial impact on HFpEF by influencing other organ systems and mitigating comorbid conditions that contribute to its progression, including metabolic dysfunction-associated steatotic liver disease (MASLD), chronic kidney disease, and pulmonary disorders

The dosage of semaglutide is dependent on each patients medical condition