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Agency for Healthcare Research and Quality

The increasing knowledge regarding heterogeneity in metabolic phenotypes is leading to the establishment of precision medicine approaches to match individuals to appropriate therapeutic mechanisms, considering their own traits, such as appetite regulation behavior, postprandial glucose levels, and genetics associated with drug metabolism and effectiveness

Beyond weight loss, tirzepatide also demonstrated significant improvements in fasting insulin, blood pressure, lipid profiles, and overall glycaemic control, reinforcing its potential role in long-term metabolic health management