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used to baseline weight and labs Phase Treatment Duration 24 weeks Notes Once-daily tablet at the assigned dose, alongside calorie-restricted diet Phase Open-label extension (TIPO-4) Duration Up to 48 additional weeks Notes Continued 0.5 mg with optional up-titration to 1.0 mg in some patients Most published efficacy comes from the 24-week treatment window

it is essentially sodium-free

If you plan to resume, restart at the full dose rather than titrating back up, since the break period allows receptor resensitization

Therefore, many studies reported that T2DM patients were associated with developing serious complications during SARS-CoV-2 infection (Batista et al