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KPV may round out the anti-inflammatory profile of the KLOW Blend through a distinct route, as suggested by laboratory work by Dalmasso et al., who posit that KPV may enter epithelial and immune cell cultures through the PepT1 transporter and, once inside, may suppress inflammatory signaling

Sodium oxybate is a sodium salt of gamma-hydroxybutyrate (a short-chain fatty acid), which is a neurotransmitter synthesized from its precursor gamma amino butyric acid (GABA)

5,6 Furthermore, measurements of metabolites such as methylmalonic acid and homocysteine have been shown to be more sensitive in the diagnosis of vitamin B 12 deficiency than measurement of serum B 12 levels alone

and track standardized outcomes (pain, function, mobility, gut symptoms) over time