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Other important safety considerations include injection site reactions, increased heart rate (a class effect, though potentially more pronounced with liraglutide), and risk of pancreatitis (which requires immediate discontinuation if suspected)

For this reason, its crucial not to store semaglutide in a freezer

The 3,533 adults from 387 sites in 28 countries, including the UK, who underwent randomisation 1,767 in the semaglutide group and 1,766 in the placebo group were followed up after a median of 3.4 years