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individuals with higher BMI or obese people have triggered some common health issues including premature mortality, cardiac diseases, high BP, worsened osteoarthritis, diabetes and in some cases cancers
Metformins most common complaints are stomach upset and diarrhea, especially when starting or increasing the dose, along with a rare but serious risk of lactic acidosis in people with significant kidney impairment
Thorens B, Porret A, Bhler L, Deng SP, Morel P, Widmann C
The PPI network of the target genes was created using STRING ( and the pathways were assessed via Reactome analysis for enrichment
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