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Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

Clinical outcomes depend on dose, consistency, and patient biology rather than brand name

[7] Ye Z, et al

Energy Production: It protects the mitochondria, the power plants of our cells, ensuring they can produce energy efficiently