can semaglutide make you infertile Cause Infertility? Evidence and Guidance Can GLP-1 Medications Improve Fertility?

Oxidative Medicine and Cellular Longevity, 2012, Article 324832

By inhibiting PI3K/Akt and MAPK/ERK pathways, IGF-1 Des is applied to explore the mechanism of intrinsic proliferation, differentiation, metabolism regulation and tissue remodeling in experimental models

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Genta administration led to a substantial increase in both caspase-3 and pro-apoptotic BAX expression, coupled with a notable decrease in anti-apoptotic Bcl-2 expression, suggesting activation of the apoptotic pathway in Genta-induced renal injury