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Liraglutide shows no effect on motor neuron count, or glial responses in the lumbar spinal cord of SOD1 G93A transgenic mice Since there was no effect of liraglutide on behavioural parameters we examined pathology in lumbar spinal cord from the end of the study when the SOD1 G93A transgenic mice were 90 days old

Importantly, the observed attenuation of incremental benefit at higher doses for both agents suggests diminishing returns with dose escalation, reinforcing the need to balance expected benefit against treatment burden and patient-specific factors

It acts as a signaling molecule involved in various cellular processes

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