This means that AOD-9604: Does not raise IGF-1 , no systemic anabolic effect Does not cause insulin resistance , a frequent side effect of high doses of hGH Has no growth effect , no influence on the growth of bones, soft tissues, organs Does not cause acromegaly , because it does not act as GH It is one of the few molecules where we have managed to surgically separate one effect of GH (lipolysis) from the others
Groups at increased risk of B12 deficiency include: Vegans and strict vegetarians , who avoid all animal products and are at significant risk without supplementation or fortified foods Older adults , in whom reduced stomach acid production impairs B12 absorption People with pernicious anaemia , an autoimmune condition that destroys intrinsic factor-producing cells Those who have undergone gastric surgery , including bariatric procedures, which can reduce intrinsic factor availability Individuals taking long-term metformin for type 2 diabetes, as this medication is associated with reduced B12 absorption the MHRA has issued specific safety advice on monitoring B12 levels in this group [6] [7] People with conditions affecting the small intestine , such as Crohn's disease or coeliac disease Symptoms of B12 deficiency can include fatigue, weakness, pins and needles, memory difficulties, and a sore or inflamed tongue (glossitis)
Oral supplements have also been shown to be effective at treating vitamin B12 deficiency
A 5mg vial, which provides approximately 10-16 days of supply at 300-500mcg daily, typically costs significantly less than GLP-1 medications
