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10.1126/science.1219855 54 ZhangH.DuanC.YangH

1 The results demonstrated that individuals treated with orforglipron displayed superior HbA 1C reduction by an average of 1.3% to 1.6% from a baseline of 8.0% compared with placebo at 40 weeks, meeting the studys primary end point

A 2025 study published in Biogerontology demonstrated dose-dependent telomere length extension in normal human cells through upregulation of hTERT (the telomerase catalytic subunit) and telomerase enzyme activity meaning Epithalon appears to reactivate the cellular machinery that maintains telomere length rather than just slowing its shortening