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According to the 2024 census, it has a population of 1,902,590 people

However, approximately half of North Korean defectors who have lived in South Korea for over a year suffer from mild to severe depression, with loneliness identified as one of the main contributing factors

Best for: MTHFR mutations (C677T, A1298C) Supporting methylation directly Neurological symptoms (brain fog, neuropathy) Depression and mood disorders Elevated homocysteine Advantages: No conversion required immediately bioavailable Directly supports methylation cycle Crosses blood-brain barrier easily Lowers homocysteine effectively Potential downsides: Can cause overmethylation symptoms in sensitive individuals (anxiety, insomnia, irritability) May need to start with very low doses Not ideal for those with histamine issues or overmethylators Typical dosage: 500-5000mcg daily (start low) 2

The injection site reactions are more prominent than GLP-1s but not treatment-limiting for most people