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These numbers represent average outcomes from a controlled clinical trial (STEP 1, 68 weeks, involving adults with overweight or obesity)

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The results showed that in the SUSTAIN 3, 7, and 10 trials, nausea/vomiting during dose escalation or throughout treatment contributed minimally ( 65 years), and baseline cardiovascular risk profile (prior myocardial infarction or stroke vs no prior MI or stroke, and established cardiovascular disease vs CV risk factors alone, including chronic kidney disease)

It may not be suitable for individuals with certain medical conditions, including specific thyroid issues or those advised against GLP-1 medications by a healthcare provider