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Work in human biopsy models has shown that IL-12p35 was not expressed within psoriatic skin lesions, whereas p40 in IL-12 and IL-23, along with IL-23p19, were significantly expressed
This happens due to electrolyte decomposition, usually triggered by overheating, over-charging, over-discharging, or physical damage
However, published scientific research has not yet shown this effect definitively
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