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Common side effects during titration include: Nausea (most common, usually improves over time) Decreased appetite Diarrhea or constipation Injection site reactions Fatigue during initial dose adjustments Timeline for Testosterone Changes Men should not expect immediate testosterone improvements from tirzepatide alone
It is the first credible argument that pharmacotherapy could compete with bariatric surgery on the only metric surgery has historically won, sheer magnitude of effect
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