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Stability & Half-Life Data Plasma half-life: Very short approximately 5-10 minutes after parenteral administration in rodent pharmacokinetic studies
They found both
The resulting mitochondrial stress activates key innate immune pathways, including cGAS-STING, TLR9, and NLRP3 inflammasome signaling, which collectively determine the balance between protective immunity and immunopathology (Xian et al., 2022)
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