Statements Author contributions FL: Software, Supervision, Methodology, Data curation, Conceptualization, Validation, Investigation, Formal Analysis, Funding acquisition, Resources, Writing review and editing, Visualization, Project administration, Writing original draft
Retatrutide activates three, targeting GLP-1, GIP, and glucagon receptors simultaneously, which is why Eli Lilly calls it a "triple agonist." This triple mechanism is also why the dose schedule matters more than with any other weight loss peptide on the market
Mental health changes should not be ignored
In the 48-week trial, weight loss had not plateaued by the end of the study in the highest dose group