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Future studies aiming at identifying global changes in gene regulation in response to prolonged exposure to GLP-1R stimulation can determine with greater detail the remaining players in the herein identified metabolic reprograming process
As a group, these compounds stimulate the production and release of HGH
Studies show the system can increase GLP-1 naturally by 54% while lowering enzymes that break it down
GLP-1 reduces endoplasmic reticulum stress and apoptosis induced by hyperglycaemia and regulates mitochondrial function via stimulation of optic atrophy protein 1 [69]
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