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Eligible publications included peer-reviewed original research articles, encompassing in vivo and in vitro experimental studies, randomized controlled trials, observational clinical studies, and mechanistically relevant translational investigations

the accumulation of reactive oxygen species (ROS) including superoxide and hydrogen peroxide, which results in lipid peroxidation and development of visible necrotic lesions (hypersensitive response, HR) ( via thiol-disulfide redox reactions (Noctor et al., 2012

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